4-HO-EPT Fumarate

Responsible Research with 4-HO-EPT

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 4-HO-EPT. Never conduct research with a chemical without learning about it first.

WARNING This product is not for human or veterinary use.

What is 4-HO-EPT?

4-Hydroxy-N-ethyl-N-propyltryptamine (also known as 4-HO-EPT or Eprocin) is a novel synthetic psychedelic substance of the tryptamine chemical class that produces psychedelic effects when administered. It is structurally related to psilocin (4-HO-DMT), the active component in psilocybin mushrooms, and produces similar effects.

Very little data exists about the pharmacological properties, metabolism, and toxicity of 4-HO-EPT. It has no history of human use before being sold online as a research chemical in 2016.[citation needed] It remains obscure and is either used recreationally or for research purposes.

Chemical Properties

4-HO-EPT, or 4-hydroxy-N,N-diethyltryptamine, is a synthetic indole molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-HO-EPT is substituted at R4 of its indole heterocycle with a hydroxyl functional group OH−. It also contains a propyl and ethyl chain bound to the terminal amine RN of its tryptamine backbone (EPT).

Pharmacological effects

Like with most psychedelic tryptamines, 4-HO-EPT is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 4-HO-EPT’s binding efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Some of the most commonly reported effects are:

• Spontaneous physical sensations
• Colour enhancement
• Pattern recognition enhancement
• Visual acuity enhancement
• Distortions
• Drifting (melting, breathing, morphing and flowing)
• Colour shifting
• Depth perception distortions
• Perspective distortions
• Symmetrical texture repetition
• Tracers
• After images
• Brightness alteration
• Diffraction
• Geometry
• Hallucinatory states
• Transformations
• Internal hallucination 
• Conceptual thinking
• Cognitive euphoria
• Delusion
• Emotion enhancement
• Immersion enhancement
• Increased music appreciation
• Memory suppression
• Ego death
• Novelty enhancement
• Personal bias suppression
• Thought loops
• Time distortion
• Enhancements
• Distortions
• Hallucinations
• Feelings of Unity and interconnectedness

Potential Side Effects

• Increased heart rate
• Nausea
• Pupil dilation

Legality

4-HO-EPT is classified as illegal in:

• Germany
• Switzerland
• United Kingdom

This list is not exhaustive, so do your own research into the legal status in your country before ordering!