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Responsible Research with Methallylescaline

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on Methallylescaline.

WARNING This product is not for human or veterinary use.

What is Methallylescaline?

4-Methallyloxy-3,5-dimethoxyphenethylamine (also known as methallylescaline and MAL) is a synthetic psychedelic substance of the phenethylamine chemical class. It is reported to produce hallucinogenic and stimulant effects comparable to that of other mescaline analogs (e.g. allylescaline, proscaline, and escaline) when administered.

The effects of methallylescaline were first described by Alexander Shulgin in his book PiHKAL: A Chemical Love Story. He lists the dosage range as 40mg to 60mg orally and describes the duration of action to be 8 – 12 hours.[1]

Very little data exists about the pharmacological properties, metabolism, and toxicity of methallylescaline, and it has little history of human usage. It is highly advised to use harm reduction practices if using this substance.

Chemical Properties

Methallylescaline, or 4-methallyloxy-3,5-dimethoxyphenethylamine, is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. Methallylescaline contains two methoxy functional groups (CH3O-) which are attached to carbons R3 and R5 of the phenyl ring.

Methallylescaline is substituted at R4 with a methallyloxy chain. This three carbon chain consists of a R2 methyl substituted allyl group with a double bond on the terminal carbon. This chain is connected to the phenyl ring at R4 through an ether (oxygen) bridge.


Pharmacological effects

Methallylescaline likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from methallylescaline’s efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Some of the most commonly reported effects are:

  • Perception of bodily lightness
  • Conceptual thinking
  • Cognitive euphoria
  • Delusion
  • Emotion enhancement
  • Immersion enhancement
  • Increased music appreciation
  • Memory suppression
  • Ego death
  • Novelty enhancement
  • Personal bias suppression
  • Thought acceleration
  • Thought loops
  • Time distortion
  • Enhancements
  • Distortions
  • Hallucinations
  • Colour enhancement
  • Pattern recognition enhancement
  • Visual acuity enhancement
  • Distortions
  • Drifting (melting, breathing, morphing, and flowing)
  • Color shifting
  • Depth perception distortions
  • Perspective distortions
  • Symmetrical texture repetition
  • Tracers
  • After images
  • Brightness alteration
  • Diffraction
  • Geometric hallucinations
  • Internal hallucination

Some of the potential side-effects include:

  • Appetite suppression
  • Frequent urination
  • Increased heart rate
  • Increased libido
  • Muscle contractions
  • Pupil dilation
  • Excessive yawning


Methallylescaline is classified as illegal in:

  • Germany
  • Switzerland
  • United Kingdom

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

How to Buy Methallylescaline

You can buy Methallylescaline and other phenethylamines like 5-MAPB, 2C-B-FLY, and 6-APB here at Chemical-Collective. All of our chemicals are third party lab tested.

All of our chemicals are strictly for research and analytical purposes only and not for human consumption.

If you wish to see NMR results for 3-FEA or any other chemical, please email us at requests@chemical-collective.com.

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All products are strictly for research purposes only and not for human consumption.

Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible

Product Name: Methallylescaline Hydrochloride

Other Name(s) 3,5-dimethoxy-4-methallyloxyphenethylamine hydrochloride

IUPAC Name 2-{3,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl}ethan-1-amine hydrochloride

CAS: 207740-41-8

Molar Mass: 287.8 g/mol

Methallylescaline HCL

, ,

3.00 / 5 (2)
- +
NMR Measurment Report
NMR Measurement
Report Available

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Sample name: ST-122 13-3-2021
Spectrometer: Bruker 500 MHz Solvent: D2O
Expected compound:
Methallylescaline HC
Identified compound:
Methallylescaline HC
Estimated purity:

Click here for the full report.

Read Reviews

2 reviews for Methallylescaline HCL

  1. Alessandro Dolcetta (verified owner)

    Sadly not that good,a lot of nausea that last all the experience and very low in visual,body high was great but nothing special

  2. Lyon4054

    Methallylescaline is a weird substance to say the least it has a exceptional strong body load which makes me not enjoy this one at all I constantly felt tired and wanted to sleep on the comeup it felt like constantly being pulled to the ground. Music grew more in the environment but just not enough for it to be amazing felt more like being teased and everything in the music felt like a constant loop, anything music related felt like taking ages a song of 3 minutes felt like 10 minutes. Visually it is a 10/10 the most amazing visuals while I had a lot of scary visuals but the times I wasn’t having scary visuals I had the most beautiful visuals I have ever experienced.

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