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5-MeO-DMT Freebase

Ratings from 21 reviews
- +

What is 5-MeO-DMT?

Important: While 5-MeO-DMT and DMT are similar chemically, they have distinct effects and safety profiles from one another, so please do not substitute 5-MeO-DMT for DMT. They should be regarded as entirely different chemicals and treated as such.

5-MeO-DMT, sometimes referred to as “The God Molecule”, is a psychedelic in the tryptamine class. It’s found naturally in a wide variety of plant species, and at least one toad species – the Sonoran Desert toad (for more information on this topic, we highly recommend Hamilton Morris’s pamphlet “Bufo Alvarius: The Psychedelic Toad of the Sonoran Desert”).

It is closely related to DMT and 5-HO-DMT, and has traditionally been used as an entheogen in South America during tribal ceremonies.

5-MeO-DMT has sharply risen in popularity over the past few years as many anecdotal reports of its potential as a healing agent have come to light. Even mainstream media outlets such as Forbes have shone a light on the healing potential of this chemical.

While research into 5-MeO-DMT is limited, some studies have supported this anecdotal evidence. In a recent prelim study, 42 participants who took 5-MeO-DMT reported lower levels of depression and anxiety as well as higher levels of life satisfaction and mindfulness. The effects persisted for at least four weeks, when a follow-up assessment was completed.

Another study surveyed 362 people who had taken 5-MeO-DMT and found that 80% of respondents reported improvements in anxiety and depression.

What are the effects of 5-MeO-DMT?

5-Meo-DMT’s psychedelic effects are thought to primarily come from its efficacy as a partial agonist at the 5-HT2A receptor. In particular, it shows a high binding affinity for the 5-HT2A and 5-HT1A subtypes. However, not much is known about these interactions so our understanding of how they result in the psychedelic experience is limited at the current time.

5-MeO-DMT is also thought to inhibit reuptake of the neurotransmitters serotonin, noradrenaline, and dopamine, but little is known about the role these mechanisms play. As such, it is strongly advised to avoid combinations with SSRIs, SRIs, MAOIs, RIMAs or any other substance that acts a releasing agent or reuptake inhibitor of monoamine neurotransmitters (serotonin and dopamine for example).

Some of the most commonly reported effects are:

  • Stimulation
  • Dissociation
  • Suppression and release of anxiety
  • Feelings of physical and cognitive euphoria
  • A sense of unity and interconnectedness
  • Catharsis
  • Emotion enhancement
  • Ego death
  • Mindfulness
  • Rejuvenation
  • Autonomous voice communication
  • Thought connectivity
  • Time distortion
  • Unity and interconnectedness

Potential Side Effects

  • Dizziness
  • Respiratory depression
  • Increased heart rate
  • Muscle contractions
  • Muscle spasms
  • Muscle tremors
  • Motor control loss
  • Nausea
  • Pupil dilation
  • Spatial disorientation


5-MeO-DMT is classified as illegal in:

  • China
  • Australia
  • Sweden
  • Turkey
  • United States

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

Responsible Research with 5-MeO-DMT

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 5-MeO-DMT, so does The Third Wave. We also have an Ultimate Guide to 5-MeO-DMT that’s well worth reading. Never conduct research with a chemical without learning about it first.

All products are strictly for research purposes only and not for human consumption.

Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible

Product Name: 5-MeO-DMT Freebase

Other Name(s): 5-methoxy-N,N-dimethyltryptamine

IUPAC Name: 3-[2-(dimethylamino)ethyl]-5-methoxyindole

CAS: 1019-45-0

Formula: C13H18N2O

Molar Mass: 218.3 g/mol

NMR Measurment Report
NMR Measurement
Report Available
Sample name: ST-113 7-3-2021
Spectrometer: Bruker 500 MHz Solvent: CDCl3
Expected compound:
Identified compound:
5-MeO-DMT freebase
Estimated purity:

Click here for the full report.

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Mykhailo L
1 day ago
On time, discreet packaging, overall 5* experience
Manuel C
1 day ago
Allí perfect
Dominik G
1 day ago
The delivery was very fast an the acid is good.
schmitt m
1 day ago
Unfortunately I have to give one star otherwise I can't send a review. I have received my first order. This amounted to around 100 euros. As a result, I placed a second order for almost 400 euros. Of course this was not sent and my x complaints were only answered with. there were difficulties.order 145400 is run dry ? scammer keep away
1 day ago
order 145061, I placed the order on 09/12, it is 09/22 and my order has still not shipped, no response from after-sales service.
1 day ago
Great stuff, idk what else to say.
John R
2 days ago
very happy
2 days ago
the service is the last. dubious and fraudulent site. I've been waiting a week for my order number 145400. When I asked, the only response I got was blah blah. tracking number doesn't work. all fake and prefabricated praise for the site. outrageous to say i like the service!!
Simon F
2 days ago
The delivery was discreet and very fast and safe delivered. I'd order again.
Nikolas A
3 days ago
Oleg W
3 days ago
simply the best! will buy again.
Jo W
4 days ago
Great great service, great product. Why go anywhere else?
Bartosz G
4 days ago
To be honest, really exceeded my expectations. The customer service is excellent, the website is beautiful and easy to navigate, the delivery time was great and the whole process of purchasing feels intuitive and clear. The products are also of impeccable quality. It's clear that the people running this service are passionate about research and amazing at what they're doing! I will definitely be a returning customer!
loison t
4 days ago
4 days ago
Noémie G
7 days ago
I ordered and payed for 5 1cp-lsd blotters, and only received 2 of them. The forms to make a complaint seemed to do not work. Nethertheless, good quality products.
Mathieu B
8 days ago
Hello, nice products like usual except Pink paillette arrive completely broken for 2 of them .... Maybe you can do something about the packaging ? and resend the 2 broken one ? thanks a lot
Jaime G
8 days ago
Faster and secure
Pierre-Louis R
9 days ago
Perfect like all the time
Luciana S
9 days ago
Eztremely efficient customer support, delivery , everything.

Lots of love
from Jack, Jessica, Gigi and Matt

Read Reviews

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28 days ago

Nice stealth, good product.

6 months ago

La livraison était rapide comme d’habitude. Rien à redire sur le service.
Le produit est de très bonne qualité. Ne pas abuser et tester avec de petites avant car il n’est pas à prendre à la légère.
Globalement, entièrement satisfait :))

8 months ago

So beautiful molecule! Be carefull, it is hugest mind changer. 😀 sitter is an obligation.

9 months ago

The most powerful thing I’ve ever seen.
The same as HCL but more difficult to use.
It’s stay in the body as a multiplier for weeks and then a small dose of lsd (150mcg) is enough and you can have full experience again like with 5-meo.

11 months ago

Me gustaría volver a probar, pero cuídense con la dosificación, es muy fuerte

11 months ago

profucto muy interesante y a la espera de volver a tenerlo

Iván Fores Palau
11 months ago

Interesante producto

1 year ago

Incredible service and product quality! Packaging, customer service, and delivery are all exceptional. The product is pure. I second the notion of preparing for dosing. I ordered a microgram scale at the same time and it is essential. The dose is not something you want to eyeball!

1 year ago

Shipped with care and kindness, with nice flyer and goodies
This substance is out of earth is outstanding when carefully dosed.

1 year ago

Phenomenal as always honestly with CC you really cant go wrong ive never been disapointed

1 year ago

An interesting but very specific substance. When ordering small quantities, you should be concerned about correct dosing beforehand, as its ‘strength’ is higher than expected from other tryptamines. The free base evaporates very easily, but also overheats easily. Susceptible individuals may experience nausea or a stomach ache and it is best to take care of this immediately so as not to ruin the research).
The delivery is brilliant!

1 year ago

Real deal. I ordered rc’s from this website of over 100€ and they always delivered. Could’nt recommend them more. + they give you cute stickers

1 year ago

Fast delivery, good quality and great customer support.

Entrega rápida, buena calidad y excelente atención al cliente.

1 year ago

OMG It’s so powerful!!!
And quality is amazing

1 year ago

Vandy vape vap emesh ss316 works great 75w 175 Celsia.. Start small be extra careful with seting safe nature far from people u may atract with unusual noise please check video to know what to expect. Much love

1 year ago

What a chem! Potent as fuck!
Careful with dosage.

1 year ago

tiene buena pinta

1 year ago

important for cc managers.
the dpd delivery company in germany may be a good option
But in Spain, the person responsible for deliveries is SEUR, which is terrible and usually has bad reviews and mistreatment with customers, there are other companies like MRW that would be more competent, I say this to help I love this page.

1 year ago

I have received it perfectly
I have not tried it yet
very professional and close, I have also received a letter about the substance with a beautiful art.
it looks good

1 year ago

Take care and let you go…. feel the univers vibrations

1 year ago

It is good old 5 Meo DMT, looks like brown sugar, 250mg is enough for at least a 100 people ! So take care and have a safe research 😉


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