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5-MeO-DMT Freebase

Ratings from 24 reviews
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What is 5-MeO-DMT?

Important: While 5-MeO-DMT and DMT are similar chemically, they have distinct effects and safety profiles from one another, so please do not substitute 5-MeO-DMT for DMT. They should be regarded as entirely different chemicals and treated as such.

5-MeO-DMT, sometimes referred to as “The God Molecule”, is a psychedelic in the tryptamine class. It’s found naturally in a wide variety of plant species, and at least one toad species – the Sonoran Desert toad (for more information on this topic, we highly recommend Hamilton Morris’s pamphlet “Bufo Alvarius: The Psychedelic Toad of the Sonoran Desert”).

It is closely related to DMT and 5-HO-DMT, and has traditionally been used as an entheogen in South America during tribal ceremonies.

5-MeO-DMT has sharply risen in popularity over the past few years as many anecdotal reports of its potential as a healing agent have come to light. Even mainstream media outlets such as Forbes have shone a light on the healing potential of this chemical.

While research into 5-MeO-DMT is limited, some studies have supported this anecdotal evidence. In a recent prelim study, 42 participants who took 5-MeO-DMT reported lower levels of depression and anxiety as well as higher levels of life satisfaction and mindfulness. The effects persisted for at least four weeks, when a follow-up assessment was completed.

Another study surveyed 362 people who had taken 5-MeO-DMT and found that 80% of respondents reported improvements in anxiety and depression.

What are the effects of 5-MeO-DMT?

5-Meo-DMT’s psychedelic effects are thought to primarily come from its efficacy as a partial agonist at the 5-HT2A receptor. In particular, it shows a high binding affinity for the 5-HT2A and 5-HT1A subtypes. However, not much is known about these interactions so our understanding of how they result in the psychedelic experience is limited at the current time.

5-MeO-DMT is also thought to inhibit reuptake of the neurotransmitters serotonin, noradrenaline, and dopamine, but little is known about the role these mechanisms play. As such, it is strongly advised to avoid combinations with SSRIs, SRIs, MAOIs, RIMAs or any other substance that acts a releasing agent or reuptake inhibitor of monoamine neurotransmitters (serotonin and dopamine for example).

Some of the most commonly reported effects are:

  • Stimulation
  • Dissociation
  • Suppression and release of anxiety
  • Feelings of physical and cognitive euphoria
  • A sense of unity and interconnectedness
  • Catharsis
  • Emotion enhancement
  • Ego death
  • Mindfulness
  • Rejuvenation
  • Autonomous voice communication
  • Thought connectivity
  • Time distortion
  • Unity and interconnectedness

Potential Side Effects

  • Dizziness
  • Respiratory depression
  • Increased heart rate
  • Muscle contractions
  • Muscle spasms
  • Muscle tremors
  • Motor control loss
  • Nausea
  • Pupil dilation
  • Spatial disorientation


5-MeO-DMT is classified as illegal in:

  • China
  • Australia
  • Sweden
  • Turkey
  • United States

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

Responsible Research with 5-MeO-DMT

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 5-MeO-DMT, so does The Third Wave. We also have an Ultimate Guide to 5-MeO-DMT that’s well worth reading. Never conduct research with a chemical without learning about it first.

All products are strictly for research purposes only and not for human consumption.

Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible

Product Name: 5-MeO-DMT Freebase

Other Name(s): 5-methoxy-N,N-dimethyltryptamine

IUPAC Name: 3-[2-(dimethylamino)ethyl]-5-methoxyindole

CAS: 1019-45-0

Formula: C13H18N2O

Molar Mass: 218.3 g/mol

NMR Measurment Report
NMR Measurement
Report Available
Sample name: AC-12 22-8-2023
Spectrometer: Bruker 600 MHz Solvent: CDCl3
Expected compound:
5-MeO-DMT freebase
Identified compound:
5-MeO-DMT freebase
Estimated purity:
5-MeO-DMT Freebase NMR paage 1

Click here for the full report.

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Stephan G
10 hours ago
Very good! It couldn't be better. Like bicycles. Highly recommended. Gladly again.
1 day ago
professionals immediate response to my payment and quick shipping
Rogelio G
1 day ago
Really good products and great customer service. ;)
Yevhenii B
2 days ago
I didn’t leave a review for a long time, because I didn’t know what I was going to work with, I was pleasantly surprised and even too surprised) the store is excellent, fast, clear and transparent)
Richard Z
2 days ago
Everything is great. Meaningful research can be only happening with high quallity chemicals. I have to say, that thanks to this company, my research got a great results. I will be ordering more for sure, we need to uncover a lot of things in our research.
Stephan G
2 days ago
4 days ago
100% trustworthy! Thank you guys!
Sergio R
4 days ago
Escribo mi reseña en español para poder expresarme con total claridad, ya que mi nivel de inglés no es muy alto. Para comenzar el servicio fue perfecto. Tardó en llegarme a Alcalá de Henares (España) tan solo 1 semana desde que realicé el pedido. La experiencia con el producto fantástica. Soy un psiconauta relativamente experto, pero es la primera vez que accedo a este tipo de productos a través de gente profesional. El viaje fue un Océano de sensaciones y percepciones únicos y maravillosos, el cual compartí con mi pareja. Nos adentramos en el bosque mientras el ácido iba haciendo su efecto sobre nosotros, resultando en una conexión extrema y placentera con la naturaleza, así como con mi compañera de viaje. Pienso repetir y volver a confiar en Chemical Collective, además de experimentar con otros productos de su catálogo
Pit F
4 days ago
5 days ago
Amazing research, thank you CC! <3
Andreas T
8 days ago
Fast delivery, impeccable service. I am happy.
8 days ago
Guys really fixed my mistake and send the order fast , so yes i have used them in the past i will use them again!Thank you team!
Vincent B
9 days ago
Very fast and effective, thx you
Roman K
9 days ago
very good resultes
Eduard C
10 days ago
I bought and everything came. Without a lie, this is the best team.
Raúl M
13 days ago
Top material very good products
14 days ago
Supberb service! 10+
Felix G
14 days ago
Every Time a great pleasure, thanks
14 days ago
Excellent shipping. High quality products.

Lots of love
from Jack, Jessica, Gigi and Matt

Read Reviews

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21 days ago

Livraison très rapide merci C.C

1 month ago

For experienced psychonauts only

3 months ago

Very very intense, I yet used only low dosages before I will get use to the feeling and lose my ego with high dosage. Sitter is very much recommended when taking bigger dosage, it is extremely potent and great substance for spiritual development.

5 months ago

Nice stealth, good product.

11 months ago

La livraison était rapide comme d’habitude. Rien à redire sur le service.
Le produit est de très bonne qualité. Ne pas abuser et tester avec de petites avant car il n’est pas à prendre à la légère.
Globalement, entièrement satisfait :))

1 year ago

So beautiful molecule! Be carefull, it is hugest mind changer. 😀 sitter is an obligation.

1 year ago

The most powerful thing I’ve ever seen.
The same as HCL but more difficult to use.
It’s stay in the body as a multiplier for weeks and then a small dose of lsd (150mcg) is enough and you can have full experience again like with 5-meo.

1 year ago

Me gustaría volver a probar, pero cuídense con la dosificación, es muy fuerte

1 year ago

profucto muy interesante y a la espera de volver a tenerlo

Iván Fores Palau
1 year ago

Interesante producto

1 year ago

Incredible service and product quality! Packaging, customer service, and delivery are all exceptional. The product is pure. I second the notion of preparing for dosing. I ordered a microgram scale at the same time and it is essential. The dose is not something you want to eyeball!

1 year ago

Shipped with care and kindness, with nice flyer and goodies
This substance is out of earth is outstanding when carefully dosed.

1 year ago

Phenomenal as always honestly with CC you really cant go wrong ive never been disapointed

1 year ago

An interesting but very specific substance. When ordering small quantities, you should be concerned about correct dosing beforehand, as its ‘strength’ is higher than expected from other tryptamines. The free base evaporates very easily, but also overheats easily. Susceptible individuals may experience nausea or a stomach ache and it is best to take care of this immediately so as not to ruin the research).
The delivery is brilliant!

1 year ago

Real deal. I ordered rc’s from this website of over 100€ and they always delivered. Could’nt recommend them more. + they give you cute stickers

1 year ago

Fast delivery, good quality and great customer support.

Entrega rápida, buena calidad y excelente atención al cliente.

1 year ago

OMG It’s so powerful!!!
And quality is amazing

1 year ago

Vandy vape vap emesh ss316 works great 75w 175 Celsia.. Start small be extra careful with seting safe nature far from people u may atract with unusual noise please check video to know what to expect. Much love

1 year ago

What a chem! Potent as fuck!
Careful with dosage.

2 years ago

tiene buena pinta

2 years ago

important for cc managers.
the dpd delivery company in germany may be a good option
But in Spain, the person responsible for deliveries is SEUR, which is terrible and usually has bad reviews and mistreatment with customers, there are other companies like MRW that would be more competent, I say this to help I love this page.

2 years ago

I have received it perfectly
I have not tried it yet
very professional and close, I have also received a letter about the substance with a beautiful art.
it looks good

2 years ago

Take care and let you go…. feel the univers vibrations

2 years ago

It is good old 5 Meo DMT, looks like brown sugar, 250mg is enough for at least a 100 people ! So take care and have a safe research 😉


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