5-MeO-DMT Freebase
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What is 5-MeO-DMT?
Important: While 5-MeO-DMT and DMT are similar chemically, they have distinct effects and safety profiles from one another, so please do not substitute 5-MeO-DMT for DMT. They should be regarded as entirely different chemicals and treated as such.
5-MeO-DMT, sometimes referred to as “The God Molecule”, is a psychedelic in the tryptamine class. It’s found naturally in a wide variety of plant species, and at least one toad species – the Sonoran Desert toad (for more information on this topic, we highly recommend Hamilton Morris’s pamphlet “Bufo Alvarius: The Psychedelic Toad of the Sonoran Desert”).
It is closely related to DMT and 5-HO-DMT, and has traditionally been used as an entheogen in South America during tribal ceremonies.
5-MeO-DMT has sharply risen in popularity over the past few years as many anecdotal reports of its potential as a healing agent have come to light. Even mainstream media outlets such as Forbes have shone a light on the healing potential of this chemical.
While research into 5-MeO-DMT is limited, some studies have supported this anecdotal evidence. In a recent prelim study, 42 participants who took 5-MeO-DMT reported lower levels of depression and anxiety as well as higher levels of life satisfaction and mindfulness. The effects persisted for at least four weeks, when a follow-up assessment was completed.
Another study surveyed 362 people who had taken 5-MeO-DMT and found that 80% of respondents reported improvements in anxiety and depression.
What are the effects of 5-MeO-DMT?
5-Meo-DMT’s psychedelic effects are thought to primarily come from its efficacy as a partial agonist at the 5-HT2A receptor. In particular, it shows a high binding affinity for the 5-HT2A and 5-HT1A subtypes. However, not much is known about these interactions so our understanding of how they result in the psychedelic experience is limited at the current time.
5-MeO-DMT is also thought to inhibit reuptake of the neurotransmitters serotonin, noradrenaline, and dopamine, but little is known about the role these mechanisms play. As such, it is strongly advised to avoid combinations with SSRIs, SRIs, MAOIs, RIMAs or any other substance that acts a releasing agent or reuptake inhibitor of monoamine neurotransmitters (serotonin and dopamine for example).
Some of the most commonly reported effects are:
- Stimulation
- Dissociation
- Suppression and release of anxiety
- Feelings of physical and cognitive euphoria
- A sense of unity and interconnectedness
- Catharsis
- Emotion enhancement
- Ego death
- Mindfulness
- Rejuvenation
- Autonomous voice communication
- Thought connectivity
- Time distortion
- Unity and interconnectedness
Potential Side Effects
- Dizziness
- Respiratory depression
- Increased heart rate
- Muscle contractions
- Muscle spasms
- Muscle tremors
- Motor control loss
- Nausea
- Pupil dilation
- Spatial disorientation
Legality
5-MeO-DMT is classified as illegal in:
- China
- Australia
- Sweden
- Turkey
- United States
This list is not exhaustive, so do your own research into the legal status in your country before ordering!
Responsible Research with 5-MeO-DMT
Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 5-MeO-DMT, so does The Third Wave. We also have an Ultimate Guide to 5-MeO-DMT that’s well worth reading. Never conduct research with a chemical without learning about it first.
All products are strictly for research purposes only and not for human consumption.
Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible
Product Name: 5-MeO-DMT Freebase
Other Name(s): 5-methoxy-N,N-dimethyltryptamine
IUPAC Name: 3-[2-(dimethylamino)ethyl]-5-methoxyindole
CAS: 1019-45-0
Formula: C13H18N2O
Molar Mass: 218.3 g/mol
Report Available
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GUIDES, INFO & REPORTS
Małgorzata Sajewiec (verified owner) –
One of my favorites I felt humility for the first time in my life but also o Great power of my minds and power as a human being. the relationship with my cat has also improved I have the impression that now I understand her better and she understands me better overall we get along better. I realized that every beings have this same goal and attitude, and the most important things is love, frendship and belonging lovelly comunity
Bek (verified owner) –
Une bénédiction nommée microdosage : l’expérience incroyable de la molécule du crapaud 🌿
Récemment, j’ai tenté un microdosage avec la fameuse molécule du crapaud, et le résultat a été tout simplement incroyable. Alors qu’à des doses importantes, cette molécule provoque une spirale vertigineuse qui plonge directement dans l’inconscient, rectifiant des problématiques émotionnelles et spirituelles en profondeur, en microdosage, c’est une autre forme de magie qui opère.
À chaque déséquilibre énergétique ou émotionnel, la molécule agit comme un rééquilibrage parfait, rapide et presque instantané. C’est comme si chaque petite perturbation trouvait automatiquement son ajustement, laissant place à un sentiment d’harmonie et de bien-être immédiat.
Cette expérience m’a ouvert les yeux sur l’immense potentiel de cette substance en petites doses. C’est une véritable bénédiction d’avoir croisé sa route, et je suis convaincu que son usage peut transformer bien des vies en apportant ce rééquilibrage subtil mais profond.
K143 –
Works like a charm. 20 mg sent me to the moon, reset my mind, bad thoughts. Felt synergy with everything, everyone. Basically like a good therapy.
Smolg –
Wow, i had a truly mesmerizing experience whit this. Definitely really good quality.
Alexandra Procházková –
Opravdu síla, jeden z nejzajímavějších testů. Není to ale pro každého, nedoporučuji zkoušet o samotě. Chemical collective děkuju!<3
monikajakobkova –
Thank you chemical-collective.com! you are special and I love you <3
If you are wondering whether microdosing is worth it, don't be afraid, it does wonders for your normal life. be sure to be careful with the dose when microdosing. taking a normal dose gave me birth again, although I don't know yet in what world I am beautiful and happy.
Małgorzata Sajewiec (verified owner) –
It’s improve my memory skills and help me with self confidence
Martin123456 –
Save Sonoran Desert Toad, go synthetic 5-MeO-DMT. Deep, powerful and ego dissolving.
MrZer0 (verified owner) –
Utterly mindblowing stuff, words can not describe the experience.
To be researched with a healthy dose of care and respect, but definitely worth exploring.
Jp (verified owner) –
Livraison très rapide merci C.C
Ben (verified owner) –
For experienced psychonauts only
Dale –
Could you tell me how to use it properly?
Voitechus –
Read reddit and erowid reports and find tripsitter! Also youtube has many tripreports, you can check it out.
Ben (verified owner) –
This is very powerful, you need to find a faciltator if you’re not experienced with this, it can be dangerous. This is not a drug, it is a cure for your mind.
voitechus –
Very very intense, I yet used only low dosages before I will get use to the feeling and lose my ego with high dosage. Sitter is very much recommended when taking bigger dosage, it is extremely potent and great substance for spiritual development.
chatack (verified owner) –
Nice stealth, good product.
Miguel91 (verified owner) –
La livraison était rapide comme d’habitude. Rien à redire sur le service.
Le produit est de très bonne qualité. Ne pas abuser et tester avec de petites avant car il n’est pas à prendre à la légère.
Globalement, entièrement satisfait :))
JanHa (verified owner) –
So beautiful molecule! Be carefull, it is hugest mind changer. 😀 sitter is an obligation.
R3RED7 –
The most powerful thing I’ve ever seen.
The same as HCL but more difficult to use.
It’s stay in the body as a multiplier for weeks and then a small dose of lsd (150mcg) is enough and you can have full experience again like with 5-meo.
aski12345a –
Me gustaría volver a probar, pero cuídense con la dosificación, es muy fuerte
aski12345a –
profucto muy interesante y a la espera de volver a tenerlo
Iván Fores Palau –
Interesante producto
bonanus –
Incredible service and product quality! Packaging, customer service, and delivery are all exceptional. The product is pure. I second the notion of preparing for dosing. I ordered a microgram scale at the same time and it is essential. The dose is not something you want to eyeball!
Ebij –
Shipped with care and kindness, with nice flyer and goodies
This substance is out of earth is outstanding when carefully dosed.
barry (verified owner) –
Phenomenal as always honestly with CC you really cant go wrong ive never been disapointed
Loiso –
An interesting but very specific substance. When ordering small quantities, you should be concerned about correct dosing beforehand, as its ‘strength’ is higher than expected from other tryptamines. The free base evaporates very easily, but also overheats easily. Susceptible individuals may experience nausea or a stomach ache and it is best to take care of this immediately so as not to ruin the research).
The delivery is brilliant!
ShiningStar (verified owner) –
Real deal. I ordered rc’s from this website of over 100€ and they always delivered. Could’nt recommend them more. + they give you cute stickers
Yabumethod –
Fast delivery, good quality and great customer support.
Entrega rápida, buena calidad y excelente atención al cliente.
ZalupaBolshayaUMenya –
OMG It’s so powerful!!!
And quality is amazing
Zes –
Vandy vape vap emesh ss316 works great 75w 175 Celsia.. Start small be extra careful with seting safe nature far from people u may atract with unusual noise please check video to know what to expect. Much love
Shulg –
What a chem! Potent as fuck!
Careful with dosage.
Jimmy420 –
tiene buena pinta
geloloco (verified owner) –
important for cc managers.
the dpd delivery company in germany may be a good option
But in Spain, the person responsible for deliveries is SEUR, which is terrible and usually has bad reviews and mistreatment with customers, there are other companies like MRW that would be more competent, I say this to help I love this page.
Jack –
Thanks for the suggestion! We will look into other options for Spain if DPD is very unreliable.
The other options we can use are GLS or PostNL (which usually uses the national postal service of the destination country). Let us know if you think they would be better!
geloloco (verified owner) –
I have received it perfectly
I have not tried it yet
very professional and close, I have also received a letter about the substance with a beautiful art.
it looks good
aliendope (verified owner) –
Take care and let you go…. feel the univers vibrations
Nilhuse721 (verified owner) –
It is good old 5 Meo DMT, looks like brown sugar, 250mg is enough for at least a 100 people ! So take care and have a safe research 😉