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3-HO-PCP HCL

12.00180.00
Ratings from 14 reviews
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FREE EXCLUSIVE PRODUCT INFO CHEMCARD WITH EVERY ORDER!!

Printed on premium card with copper foil inlay, soft-touch lamination, and exclusive custom artwork.

Have a look at them here.

Responsible Research with 3-HO-PCP

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 3-HO-PCP.

WARNING This product is not for human or veterinary use.

What is 3-HO-PCP?

3-Hydroxyphencyclidine (commonly known as 3-HO-PCP) is a novel dissociative substance of the arylcyclohexylamine class that produces potent dissociative, hallucinogenic and euphoric effects when administered. In addition to its primary activity as a NMDA receptor antagonist, it has been found to have appreciable affinity for the μ-opioid receptor.

3-HO-PCP was first synthesized in 1978 to investigate the structure-activity relationship of phencyclidine (PCP) derivatives. It was further explored alongside PCP in the 1980s, where it was discovered to possess μ-opioid agonist activity in animal models.

Like other substances of its class, particularly methoxetamine (MXE), phencyclidine (PCP), and 3-MeO-PCE, it is known to primarily induce a state referred to as “dissociative anesthesia”, albeit the extent to which this occurs has been reported to be highly dose-dependent and variable in its effects. It is unknown whether the studied opioid properties in animal models applies to humans, with some early reports suggesting that it does not.

Today, 3-HO-PCP is almost exclusively distributed as a gray area research chemical by online vendors. Extremely little is known about its pharmacology, metabolism and toxicity in humans. Due to its sensitive dose-response, potential habit-forming properties, as well as unknown toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance.

Chemical Properties

3-HO-PCP, or 3-hydroxyphencyclidine, is a synthetic dissociative of the arylcyclohexylamine class. The structure of 3-HO-PCP consists of cyclohexane, a six-membered saturated ring, bonded to two additional rings at R1. One of these rings is a piperidine ring, a nitrogenous six member ring, bonded at its nitrogen group. The other ring is an aromatic phenyl ring, substituted at R3 with a hydroxy group.

3-HO-PCP is a structural analog of PCP and a homolog 3-MeO-PCP.

Pharmacological effects

Like other arylcyclohexylamine dissociatives, 3-HO-PCP acts principally as an NMDA receptor antagonist. The NMDA (N-Methyl-D-Aspartate) receptor, a specific subtype of the glutamate receptor, modulates the transmission of electrical signals between neurons in the brain and spinal cord; for the signals to pass, the receptor must be open. Dissociatives inhibit the normal functioning NMDA receptors by binding to and blocking them. This disruption of neural network activity causes network disintegration, some research suggests, by hyperconnectivity throughout the brain. This causes an increase in noise (random, nonsensical and erroneous data) on the cerebral network and thus produces loss of normal cognitive and affective processing, psychomotor functioning, anesthesia. This is often observed in those showing psychosis or induced with high-dose IV THC or Ketamine in healthy participants.

Unlike many other dissociatives, 3-HO-PCP has also been found to have appreciable affinity as a μ-opioid receptor agonist in animal models. However, the extent to which this applies to humans remains unknown.

Some of the most commonly reported effects are:

  • Stimulation
  • Spontaneous bodily sensations
  • Anxiety suppression
  • Physical & cognitive euphoria
  • Tactile enhancement 

Potential Side Effects

  • Sedation
  • Conceptual thinking
  • Déjà vu
  • Orgasm suppression
  • Ego death

Legality

3-HO-PCP is classified as illegal in:

  • United Kingdom
  • Switzerland
  • Sweden
  • Turkey

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

How to Buy 3-HO-PCP

You can buy 3-HO-PCP and other dissociatives like 3-HO-PCE, 3-MeO-PCP, and DCK here at Chemical-Collective. All of our chemicals are third party lab tested.

All of our chemicals are strictly for research and analytical purposes only and not for human consumption.

If you wish to see NMR results for 3-HO-PCP or any other chemical, please email us at requests@chemical-collective.com.

All products are strictly for research purposes only and not for human consumption.

Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible

Product Name: 3-HO-PCP hydrochloride

Other Name(s): 3-hydroxyphencyclidine hydrochloride

IUPAC Name: 1-[1-(3-hydroxyphenyl)cyclohexyl]-piperidine hydrochloride

CAS: 79787-43-2

Molar Mass: 295.9 g/mol

NMR Measurment Report
NMR Measurement
Report Available
Sample name: AC-01 10-5-2023
Spectrometer: Bruker 600 MHz Solvent: D2O
Expected compound:
3-HO-PCP HCL
Identified compound:
3-HO-PCP HCL
Estimated purity:
99%
NMR Analysis Report Screenshot

Click here for the full report.

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person
Mykhailo L
1 day ago
On time, discreet packaging, overall 5* experience
person
Manuel C
1 day ago
Allí perfect
person
Dominik G
1 day ago
The delivery was very fast an the acid is good.
person
schmitt m
1 day ago
Unfortunately I have to give one star otherwise I can't send a review. I have received my first order. This amounted to around 100 euros. As a result, I placed a second order for almost 400 euros. Of course this was not sent and my x complaints were only answered with. there were difficulties.order 145400 is run dry ? scammer keep away
person
Greg
1 day ago
order 145061, I placed the order on 09/12, it is 09/22 and my order has still not shipped, no response from after-sales service.
person
LAQYGSEJ M
1 day ago
Great stuff, idk what else to say.
person
John R
2 days ago
very happy
person
Marc
2 days ago
the service is the last. dubious and fraudulent site. I've been waiting a week for my order number 145400. When I asked, the only response I got was blah blah. tracking number doesn't work. all fake and prefabricated praise for the site. outrageous to say i like the service!!
person
Simon F
2 days ago
The delivery was discreet and very fast and safe delivered. I'd order again.
person
Nikolas A
3 days ago
Great
person
Oleg W
3 days ago
simply the best! will buy again.
person
Jo W
4 days ago
Great great service, great product. Why go anywhere else?
person
Bartosz G
4 days ago
To be honest, really exceeded my expectations. The customer service is excellent, the website is beautiful and easy to navigate, the delivery time was great and the whole process of purchasing feels intuitive and clear. The products are also of impeccable quality. It's clear that the people running this service are passionate about research and amazing at what they're doing! I will definitely be a returning customer!
person
loison t
4 days ago
:)
person
Elsa
4 days ago
Reliable
person
Noémie G
7 days ago
I ordered and payed for 5 1cp-lsd blotters, and only received 2 of them. The forms to make a complaint seemed to do not work. Nethertheless, good quality products.
person
Mathieu B
8 days ago
Hello, nice products like usual except Pink paillette arrive completely broken for 2 of them .... Maybe you can do something about the packaging ? and resend the 2 broken one ? thanks a lot
person
Jaime G
8 days ago
Faster and secure
person
Pierre-Louis R
9 days ago
Perfect like all the time
person
Luciana S
9 days ago
Eztremely efficient customer support, delivery , everything.

Lots of love
from Jack, Jessica, Gigi and Matt

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mhdismailali
26 days ago

very pure product, excellent quality

Jfraktal
9 months ago

Good quality!
Be sure tu use precision scale ’cause the dosage is very low.
A strong euphoria, energic and trippy experience with this molecule.
But if you take too much it can be maniac, overstimulated and bad mood going on, take care with research!

LampkaNocna
10 months ago

Fast shipping , great product , although I don’t like the effects of this product in research

Oeleiop
11 months ago

Feels very clean, quite sedating

willy
1 year ago

super produit

willy
1 year ago

produit de très bonne qualité

nDee
1 year ago

Just a small sniff of truth..is that for children? My cat was yawning 😉

MikePL
1 year ago

The purity of the material is stunning. HI TEC.

Forestakias
1 year ago

Warm, clearheaded, no confusion or paranoia. This and DCK are thw GOAT 👽👽👽

Dr Dylan
1 year ago

In my opinion one of the best dissos i ever had around 7mg insuflated ! A blast ! Lasted pretty long, like sweet waves, pretty strong for so few.. i recommend strongly 😉

darke707
2 years ago

A-fuckin-mazing!

Jzack
3 years ago

Excellent. What I asked for. Lasted for many sessions of research. Overall good.

ChickenCobra
3 years ago

High quality product. Well Tested!

Sjofn
3 years ago

that goood goooooooooooooood

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