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Responsible Research with DMXE

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. DMXE is an extremely novel chemical, so use the utmost caution during your experiments. Never conduct research with a chemical without learning about it first.

What is DMXE?

DMXE is a dissociative substance of the arylcyclohexylamine class that produces dissociative, anesthetic, stimulating and hallucinogenic effects when administered

It was believed to have been first synthesised by a laboratory in the Netherlands in 2020. 

Little is known about DMXE due to its relative novelty, so we will provide information about the chemical class it belongs to – arylcyclohexylamines.

Chemical Properties

DMXE is an arylcyclohexylamine dissociative. An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamino or ethylamino, or tertiary cycloalkylamines such as piperidino and pyrrolidino, are the most commonly encountered N-substituents.

Pharmacological effects

Initial reports suggest that DMXE shares many subjective properties with MXE. More-so than other chemicals such as MXPr, MXiPr and DCK.

Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based on its structure and subjective effect similarities to other arylcyclohexylamine dissociatives such as ketamine, PCE and methoxetamine (3-MeO-2′-Oxo-PCE). While no scientific studies have been conducted to verify this, structure-activity relationship analysis suggests that 2′-Oxo-PCE likely exhibits its observed effects principally as an NMDA receptor antagonist, although other neurotransmitter systems may be involved.

NMDA receptors (a subtype of receptors for glutamate, which are the principal excitatory neurotransmitters in the nervous system) allow for electrical signals to pass between nerve cells in the brain and spinal column; for the signals to pass, the receptor must be open. NMDA receptor antagonists have been shown to disrupt this signaling by blocking these receptors. This disconnection of information flow in the nervous system leads to loss of sensation (anesthesia), difficulty moving (motor discoordination), and eventually this substance’s equivalent of the “K-hole.”

Some of the most commonly reported effects are:

  • Stimulation
  • Perception of bodily lightness
  • Physical autonomy
  • Physical euphoria
  • Dissociation
  • Enhanced proprioception

Potential Side Effects

  • Lightheadedness
  • Dizziness
  • Motor control loss
  • Orgasm suppression
  • Mania


DMXE is classified as illegal in:

  • United Kingdom

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

Read More

All products are strictly for research purposes only and not for human consumption.

Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible

Product Name: DMXE Hydrochloride 40mg Pellets

Other Name(s): Deoxymethoxetamine, 3D-MXE, methetamine, 3-Me-2′-oxo-PCE Hydrochloride

IUPAC Name: 2-(ethylamino)-2-(3-methylphenyl)-cyclohexanone hydrochloride


Molar Mass: 267.8 g/mol

DMXE 40mg Pellets

, ,

4.88 / 5 (16)
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NMR Measurment Report
NMR Measurement
Report Available

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Sample name: ST-213 20-07-22
Spectrometer: Bruker 600 MHz Solvent: CDCl3
Expected compound:
Identified compound:
Estimated purity:
DMXE NMR Report Screenshot

Click here for the full report.

Read Reviews

16 reviews for DMXE 40mg Pellets

  1. egg2020

    I got two pills and took them both at once, it seemed really nice and pleasant but the effects were very short-lived
    I’ll definitely be more interested in researching more of it in the future!

  2. beatlee

    jest ok

  3. Tetanoss (verified owner)

    Good stuff, pleasant and strong effect. 1 is more than enough. Effects last approximately 1 hour.

  4. Diego

    Me gusta muchísimo y volvere a comprar

  5. Diego

    Tengo que probar esto con amigos

  6. abdissar

    That stuff is pretty strong, and oh boy, my test subjects do love it.

  7. avery

    extremely warm and ”fuzzy” disso, with no tolerance is pretty potent.

  8. Lucasyn

    Really interesting substance

  9. VJBs (verified owner)

    Top quality product! At first it seemed that it was less effective than in hcl form. But I was wrong! After resetting tolerance only 20mgs gave me wonderful researches and 40 mgs were the top! No need to go further!

    PS: I don’t know if it could be a bias put I always burn some incence in the lab while doing research.

  10. Nilhuse721 (verified owner)

    Little bit less potent then HCL but does the job right !!

  11. M

    Gute Qualität, Sehr interessantes Produkt!

  12. Noir (verified owner)

    Effekte von sehr kurzer Dauer, das Potenzial war aber erahnbar. Bei meinem Test waren 40mg aber scheinbar zu niedrig. Preis/Gram verhältnis dürfte beim HCL Puder besser sein. Verträglichkeit ist aber gut.

  13. Moravia

    Very nice molecules
    Sweet in a half – truly good in one – creative in oneandahalf

  14. Schnoz

    Sehr interessantes Produkt, habe schon einige Tests damit gemacht und muss sagen, ich bin mehr als überzeugt. Sehr schade dass dieses Produkt wegen dem NpSG demnächst verboten wird, werde auf jeden fall etwas aufstocken und empfehle auch anderen dasselbe zu tun!

  15. M

    I’ve only tested 1/4 so far, but I have to say it’s a very interesting substance.

  16. Chris Saey (verified owner)

    Gewohnt hochwertige Qualität von Liazard Labs, und ein sehr angenehmes Produkt muss ich sagen.

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