Welcome to
Chemical Collective

Are you 18 or older?

Please confirm that your are 18 years of age or older.

You are not allowed to access the page.

Friendly customer service available 9am-5pm Monday to Friday

Free standard shipping over €50 and free tracked shipping over €100

Cart
  • 1D-LSD

    1D-LSD 150mcg Blotters - 2

    1 X 29.00

Total 29.00

3-HO-PCE HCL

18.0090.00
Ratings from 1 reviews
- +

Responsible Research with 3-HO-PCE

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 3-HO-PCE, so does The Third Wave. Never conduct research with a chemical without learning about it first.
!
WARNING This product is not for human or veterinary use.

What is 3-HO-PCE?

3-Hydroxyeticyclidine (commonly known as 3-HO-PCE) is a novel synthetic dissociative substance of the arylcyclohexylamine chemical class. It produces potent, dose-sensitive dissociative, hallucinogenic and euphoric effects when administered. Unlike its close structural analog 3-HO-PCP, this compound has no precedent in the scientific literature before being offered on the research chemicals market in the 2010s.

Early discussions of this compound have revolved around whether it possesses an appreciable affinity for the μ-opioid receptor given its structural relationship to 3-HO-PCP, which has been shown to display affinity for the μ-opioid receptor in animal models. Whether it produces any of its theorized opioid effects in humans is the subject of ongoing discussion. If it does, 3-HO-PCE may pose unique risks relative to other dissociatives, particularly when it is redosed.

Following other substances of its class, particularly methoxetamine (MXE), phencyclidine (PCP), and 3-MeO-PCE, it is speculated to be able to induce a state known as “dissociative anesthesia”. Early reports suggest that this state is difficult to reach relative to other dissociatives, and its general effects profile has been characterized as “lying halfway between 3-MeO-PCP and 3-MeO-PCE.”

Chemical Properties

3-HO-PCE, or 3-hydroxyeticyclidine, is a synthetic dissociative of the arylcyclohexylamine class. The structure of 3-HO-PCE is composed of cyclohexane, a six-membered saturated ring, bonded to two additional groups at R1. One of these an ethyl chain bonded to its nitrogen group. The other ring is an aromatic phenyl ring, substituted at R3 with a hydroxy group.

3-HO-PCE is an analog of PCE and structurally homologous to 3-MeO-PCE.

Pharmacological effects

While no formal studies have been conducted, 3-HO-PCE likely acts principally as an NMDA receptor antagonist.

The NMDA (N-Methyl-D-Aspartate) receptor, a specific subtype of glutamate receptor, modulates the transmission of electrical signals between neurons in the brain and spinal cord; for the signals to pass, the receptor must be open.

Dissociatives inhibit the normal functioning NMDA receptors by binding to and blocking them. This disruption of neural network activity leads to loss of normal cognitive and affective processing, psychomotor functioning, anesthesia.[citation needed]

There is ongoing speculation as to whether this compound possesses μ-opioid receptor activity due to its structural relationship to 3-HO-PCP, which has been found to have appreciable affinity as a μ-opioid receptor agonist in animal models.

Some of the most commonly reported effects are:

  • Tactile suppression 
  • Stimulation & Sedation
  • Pain relief 
  • Changes in felt gravity
  • Conceptual thinking

Potential Side Effects

  • Difficulty urinating
  • Mania
  • Time distortion
  • Appetite suppression
  • Psychosis

Legality

3-HO-PCE is classified as illegal in:

  • United Kingdom
  • Turkey

This list is not exhaustive, so do your own research into the legal status in your country before ordering!

How to Buy 3-HO-PCE

You can buy 3-HO-PCE and other dissociatives like 3-HO-PCP, 3-MeO-PCP, and DCK here at Chemical-Collective. All of our chemicals are third party lab tested.

All of our chemicals are strictly for research and analytical purposes only and not for human consumption.

If you wish to see NMR results for 3-HO-PCE or any other chemical, please email us at requests@chemical-collective.com.

All products are strictly for research purposes only and not for human consumption.

Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20'c where possible

Product Name: 3-HO-PCE hydrochloride

Other Name(s): 3-Hydroxyeticyclidine

IUPAC Name: 3-[1-(Ethylamino)cyclohexyl]phenol

Molecular Formula: C14H21NO

CAS: N/A

Molar Mass: 255.8 g/mol

NMR Measurment Report
NMR Measurement
Report Available
Sample name: ST-105 7-3-2021
Spectrometer: Bruker 500 MHz Solvent: D2O
Expected compound:
3-HO-PCE
Identified compound:
3-HO-PCE salt
Estimated purity:
>99%

Click here for the full report.

our products

Related products

1D-LSD 150mcg Blotters 29.001,475.00
(60)
2-FDCK HCL
9.501,800.00
7.601,440.00
(69)
1V-LSD 150mcg Blotters 22.001,180.00
(116)
DMXE HCL 20.004,000.00
(41)
4-HO-MET Fumarate 20mg Pellets 18.00315.00
(29)
1cP-LSD 100mcg Blotters 18.00945.00
(117)
1D-LSD 10mcg Micro Pellets 12.00500.00
(18)
3-HO-PCP HCL

OUT OF STOCK

3-HO-PCP HCL 12.00180.00
(15)
1cP-LSD 10mcg Micro Pellets 12.50269.00
(18)
person
Iker R
20 hours ago
Awesome as always ❤️
person
Jaime V
22 hours ago
Perfectomundo :-)
person
Jörg S
1 day ago
Good service, thanks 👍
person
Federico M
5 days ago
Primo viaggio con 1D-LSD... Dio vi benedica, mi auguro che duriate tanto tanto tanto :)
person
Agustin
5 days ago
Not gonna lie I expected to have to wait 3 months if it even arrived with how notoriously bad my country's customs is. It arrived perfectly though in just over a month. Super excited to order again!
person
Dua M
5 days ago
So i had the worst experience with them ever. My order was not being able to be tracked down and when I contacted them they told me to check in with the post office myself. I did and got my package although it was empty and there was nothing in the packaging so the day of the party where I was supposed to use my order. did not happen so my friends were all high and I had to sit there sober because of their mistake. Upon contacting them, they replied days after and promise to double the order and send it. Well it did not happen when the order came it had the original order which was not doubled down.(eventhough it was promised ). Anyways I was scammed before so I decided to make a video before opening the package ….and u guessed it. There was nothing in it and it was caught on the camera. I wrote them an email which they have been ignoring from a while after more than a week I’m writing this review and hoping to get atleast my money back! I would suggest to avoid them at all costs!
person
Ilya M
7 days ago
100/100!
person
Headmaster257
9 days ago
I have made several orders at this store. Once the package was not delivered to me. Probably the loss of the carrier that delivered the package. Even though the package was not insured against loss, I was sent compensation in the form of a "gift" in the next order. When I pointed it out. The CC team communicates by e-mail, is happy to advise you and always accommodates your requests. The only e-shop that has soul and very good heart. Great shop, great team. Thank you very much.
person
Roman P
9 days ago
First it arrive in two weeks. For me it one of this fast shipping. Second, the material was with full.chem sticks. So you do not worry. The quality of what I had check was wonder full
person
Ole M
9 days ago
Love the site, I’d wish some more products would be added that are available in Germany.
person
Michael C
10 days ago
I had a very therapeutic experience. Felt very refreshed and healed.
person
Marko N
11 days ago
Took a bit longer to arrive than I expected but overall very good experience.
person
Frank M
11 days ago
Absolutely reliable delivery. Thank you !
person
Giovanna D
11 days ago
Update: I got a message from them.
person
François-Xavier L
12 days ago
I ordered 1cp-lsd. after a laboratory analysis, i learn’t That’s it’s 1p-lsd. I think it's not very serious
person
Víctor H
12 days ago
After one month I haven't received my order. I could understand it's not necessarily their fault but Chemical Collective did not offer any solution.
person
André J
12 days ago
Super schnelles und verlässliches Handling - gerne wieder!
person
Jim R
12 days ago
All good, fast delivery
person
Emeric C
13 days ago
Delivery in time Product of really good quality, really happy and will order again very soon big thanks to chemical collective !!
person
Witali J
14 days ago
Fantastic

Lots of love
from Jack, Jessica, Gigi and Matt

Read Reviews

Inline Feedbacks
View all comments
Nilhuse721
2 years ago

little bit less powerfull then 3 ho pcp, but really interesting results nonetheless !

rewards-icon
popup-logo

Reward program

popup-close
  • Earn
  • Affiliates